Endocrine Abstracts

Osteopetrosis and O.I. are both bone metabolic disorders with opposite features in terms of the metabolic turnover: while osteopetrozis has a low turnover and increased BMD due to the failure of osteoclasts to resorb bone, O.I. is well known as a high turnover disease with low BMD caused bt mutations in the COL1A1 and col COL1A2 genes that encode type 1 procollagen; yet, both condition, in spite of different mechanism, end up with increased ftracure prevalence. We report the c...

Introduction: Papillary thyroid carcinoma is well known as a differentiated thyroid carcinoma with an established treatment protocol and high survival rates. Poorly differentiated thyroid carcinoma, or anaplastic, is highly aggressive, manifesting with local invasion, recurrence, and distant metastasis; it is well known that these two entities may be connected as a process of dedifferentiation, most commonly met in elderly people with a long term standing untreated well differ...

Introduction: The aim of the study was to evaluate the relevance of autoimmunity in the cytological results for the thyroid nodules referred to FNAB (fine-needle aspiration biopsy).Materials and methods: Our study included 590 patients who underwent FNAC in 615 nodules between December 2015 and January 2019. Besides demographic data and routine endocrine investigations (thyroid hormonal status, presence of autoimmunity, the actual or past use of levothyr...

Introduction: The FRAX fracture risk assessment algorithm is able to integrate clinical risk factors independent of bone mineral density (BMD), evaluating the 10-years probability of fracture, therefore identifying patients in need for antiosteoporotic treatment, in which case bypassing the WHO (World Health Organization) criteria for densitometric diagnosis of osteoporosis.Material and Methods: We retrospectively analysed a total of 91 scans of women ag...

Introduction: Besides the amount of bone mineral assesed through bone mineral density (BMD), studies have shown that neck geometry parameters as hip axis length (HAL) and neck-shaft angle (NSA) could also be reliable parameters to be included in the hip fracture assesement. On the other hand, bone geometry is known to be modified in acromegaly in flat bones, thus hip fracture is not a recognized direct complication in acromegaly neither through bone mass or long bone geometry....